Cleveland Guardians at Minnesota Twins odds, picks and predictions (2024)

The Cleveland Guardians (6-2) and Minnesota Twins (3-3) play the middle contest of a 3-game series Saturday at Target Field after a scheduled day off. First pitch is scheduled for 2:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0; Cleveland spoiled the home opener for Minnesota Thursday, winning 4-2 as an underdog (+150) as the Under (7) cashed

The Guardians have won 3 in a row, each as underdogs, and Cleveland has won 6 of 8 games on the road to open the season. The Under cashed on Thursday in the series opener, which was a rarity, as the Guardians had cashed the Over at a 5-1-1 pace in the 1st 7 games.

The Twins have dropped 3 of the past 4 games after opening 2-0. Minnesota is just 2-2 as a favorite, and the Under holds a 4-2 advantage in 6 games to date. Minnesota has scored 2 or fewer runs in 3 of the previous 4 outings, including an 11-0 shutout loss in Kansas City March 31.

Guardians at Twins projected starters

RHP Carlos Carrasco vs. RHP Joe Ryan

Carrasco (0-0, 5.40 ERA) makes his 2nd start in 2024. He allowed 3 ER on 6 H and 1 BB with 3 K in 5 IP in his debut at the Oakland Athletics Sunday.

• 2023 road splits (with the Mets): 2-5, 5.44 ERA (49 2/3 IP, 30 ER — 10 HR), 18 BB, 30 K in 10 starts
• Last start vs. Twins: Loss, 6 IP, 3 ER, 6 H, 1 BB, 5 K in 3-0 loss at Target Field Aug. 1, 2020, in 1st stint with Guardians

Ryan (0-0, 1.69 ERA) makes his 2nd start in 2024. He allowed 1 ER on 3 H and 1 BB with 5 K in 5 1/3 IP in his debut at the Kansas City Royals last Saturday.

• 2023 home splits: 7-4, 3.83 ERA (82 1/3 IP, 35 ER — 12 HR), 15 BB, 111 K in 14 starts
• 2023 vs. Guardians: 0-3, 3.24 ERA (16 2/3 IP, 6 ER — 0 HR), 2 BB, 11 K in 3 starts

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! BHQ offers Draft Prep and full-season subscriptions. Sign up today and start winning!

Guardians at Twins odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:45 a.m. ET.

• Moneyline (ML): Guardians +140 (bet $100 to win $140) | Twins -165 (bet $165 to win $100)
• Run line (RL)/Against the spread (ATS): Guardians +1.5 (-140) | Twins -1.5 (+115)
• Over/Under (O/U): 8.5 (O: -110 | U: -110)

Guardians at Twins picks and predictions

Prediction

Guardians 4, Twins 3

Moneyline

The GUARDIANS (+140) are worth a look as moderate underdogs in the middle game of this set.

Last season, Ryan struggled against Cleveland, going 0-3 despite the fact he had a decent ERA at 3.24 in the 3 outings. However, the Twins (-165) have struggled against Cleveland in recent seasons, going just 3-6 in the past 9 meetings. They’re not worth playing as rather heavy favorites. Keep fading Minnesota until it starts beating Cleveland on the regular.

Run line/Against the spread

The GUARDIANS +1.5 (-140) aren’t priced out of line if you’re looking for a little insurance, and you just cannot trust the Twins -1.5 (+115).

As an underdog, Cleveland has posted a 4-1 mark in the past 5 on the run line, including 4 outright victories.

Over/Under

UNDER 8.5 (-110) cashed in the series opener Thursday while going 4-2 in the past 6 meetings and 7-3 across the past 10 battles in this series.

Cleveland’s pitching has been sharp so far, allowing 4 or fewer runs in 7 of 8 games, while allowing just 4 total runs in the previous 3 outings.

For Minnesota, it has scored just 2 or fewer runs in 3 of the past 4 outings, and Twins pitching has yielded just 4 runs or fewer in 5 of 6 games to date.

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball